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SandboxAQ

Machine Learning Scientist, Bioinformatics

Job Summary

The role involves developing and applying deep learning models to predict genomic and transcriptomic profiles, particularly in the context of drug discovery. Candidates should have a Ph.D. in computational biology, bioinformatics, or related fields, with at least two years of industry experience working on deep learning for biopharma. The position requires proficiency in software tools like Python, R, and deep learning frameworks such as PyTorch, as well as experience with large-scale GPU workloads and data curation. Applicants will collaborate with cross-functional teams, contribute to research publications, and participate in international conferences to advance AI-driven drug discovery.

Required Skills

Machine Learning
Software Development
Deep Learning
Cloud Computing
GPU Computing
Open Source Contribution
Research Communication
Bioinformatics
Computational Biology
Genomics
Transcriptomics
Spatial Transcriptomics
Data Curation
Sequence Modeling

Benefits

Paid Time Off
Stock Options
Learning opportunities
Family Planning/Fertility
Financial Wellness Resources
Medical/Dental/Vision
401(k) Plans

Job Description

About SandboxAQ

SandboxAQ is a high-growth company delivering AI solutions that address some of the world's greatest challenges. The company’s Large Quantitative Models (LQMs) power advances in life sciences, financial services, navigation, cybersecurity, and other sectors.

We are a global team that is tech-focused and includes experts in AI, chemistry, cybersecurity, physics, mathematics, medicine, engineering, and other specialties. The company emerged from Alphabet Inc. as an independent, growth capital-backed company in 2022, funded by leading investors and supported by a braintrust of industry leaders.

At SandboxAQ, we’ve cultivated an environment that encourages creativity, collaboration, and impact. By investing deeply in our people, we’re building a thriving, global workforce poised to tackle the world's epic challenges. Join us to advance your career in pursuit of an inspiring mission, in a community of like-minded people who value entrepreneurialism, ownership, and transformative impact.

About the Role

We are looking for a Bioinformatician with deep experience in the training and application of deep learning models, especially but not limited to genomics, transcriptomics, spatial transcriptomics, and related fields. As a member of the Large Quantitative Model (LQM) team, you will develop completely new computational tools to reshape drug discovery.

What You’ll Do

  • Develop and apply deep learned models to predict genomic and transcriptomic profiles, including after perturbation by drug molecules.
  • Drive curation and use of high-quality datasets, such as single-cell RNA-seq datasets.
  • Work with a cross-functional team of experts to computerize drug discovery.
  • Write patents, research papers and technical documents. Participate and present at international conferences.
  • Reshape drug discovery, advance machine learning, and protect humanity from disease.

About You

  • Ph.D. in a field setting you up to work on deep learning models for genomics, transcriptomics, and biological pathway modelling: computational biology, bioinformatics, computer science, applied math, etc.
  • 2+ years working on deep learning for biopharma in an industry context.
  • Experience in training, applying, and optimizing contemporary deep learning models, including generative models, as demonstrated by:
  • Experience applying deep learning models to problems in biopharma: genomics, transcriptomics, spatial transcriptomics, and/or related fields such as structural biology.
  • Software skills: advanced proficiency with Python, with related software ecosystem tools (i.e. Git, Docker, Kubernetes, etc), and contemporary deep learning and informatics terms (i.e. R, Pytorch, etc)
  • Excellent communication skills

Nice-to-haves

  • Relevant postdoctoral training
  • Experience in long-context sequence modeling
  • Direct experience in drug discovery or development
  • Experience running deep learning workloads on GPU clusters at large scale
  • Experience working on cloud
  • Contributions to open source repositories

The US base salary range for this full-time position is expected to be $192k - $269k per year. Our salary ranges are determined by role and level. Within the range, individual pay is determined by factors including job-related skills, experience, and relevant education or training. This role may be eligible for annual discretionary bonuses and equity.

SandboxAQ welcomes all.

We are committed to creating an inclusive culture where we have zero tolerance for discrimination. We invest in our employees' personal and professional growth. Once you work with us, you can’t go back to normalcy because great breakthroughs come from great teams and we are the best in AI and quantum technology.
We offer competitive salaries, stock options depending on employment type, generous learning opportunities, medical/dental/vision, family planning/fertility, PTO (summer and winter breaks), financial wellness resources, 401(k) plans, and more.
Equal Employment Opportunity: All qualified applicants will receive consideration regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status.
Accommodations: We provide reasonable accommodations for individuals with disabilities in job application procedures for open roles. If you need such an accommodation, please let a member of our Recruiting team know.

Interested in this job?

Application deadline: Open until filled

Logo of SandboxAQ

SandboxAQ

SandboxAQ leverages the compound effects of AI and advanced computing to address some of the biggest challenges impacting society. SandboxAQ technologies include AI simulation, cryptography management for cybersecurity, and AI sensing for global organizations.

See more jobs
Date PostedMay 14th, 2025
Job TypeFull Time
LocationRemote, USA
Salary$192,000 - $269,000
Exciting remote opportunity (requires residency in United States) for a Machine Learning Scientist, Bioinformatics at SandboxAQ. Offering $192,000 - $269,000 (full time). Explore more remote jobs on FlexHired!

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