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Natera

Senior Bioinformatician/Computational Biologist

Job Summary

Natera is seeking a Lead Bioinformatician/Computational Biologist responsible for developing and implementing NGS assays and analysis pipelines for clinical diagnostics. The role involves collaborating with wet lab scientists and clinical staff to optimize workflows and ensure successful assay deployment. Candidates should have a PhD or MS in relevant fields with extensive experience in DNA/RNA sequencing data analysis, programming, and high-performance computing environments. The position emphasizes innovation in genetic testing, teamwork across disciplines, and contributions to cutting-edge healthcare solutions.

Required Skills

Data Analysis
Programming
High-Performance Computing
Cloud Computing
Pipeline Development
Workflow Orchestration
Bioinformatics
Computational Biology
Next-Generation Sequencing
Laboratory Collaboration

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
Life Insurance
Commuter Benefits
Employee Referral Program
Fertility Benefits
Disability Plans
Pregnancy Leave
Baby Bonding Leave
401k Benefits

Job Description

About the Role

Natera is seeking an experienced Senior Bioinformatician/Computational Biologist to join our innovative team. In this role, you'll leverage your expertise in NGS, quantitative biology, and methods development to advance our high-volume clinical diagnostic sequencing initiatives.

Key Responsibilities

  • Drive the development of novel NGS assays for clinical diagnostic applications as part of a dynamic, cross-disciplinary team of molecular and computational biologists
  • Design and implement robust analysis tools and pipelines for processing diagnostic assays across tumor, germline, and cell-free DNA samples
  • Collaborate closely with wet lab scientists to build, troubleshoot, and optimize complex, high-throughput NGS workflows involving diverse sample types and analytical targets
  • Partner with clinical staff to validate and successfully deploy assays into production environments
  • Contribute expertise throughout the entire process flow—from initial sequencing through validation and production implementation

Required Qualifications

  • PhD or MS in Bioinformatics, Computational Biology, Genomics, or related field
  • 4+ years of industry experience in clinical diagnostics or related field
  • Demonstrated expertise in DNA/RNA sequencing data analysis and interpretation
  • Proficiency working with public genomics data sources (HapMap, dbSNP, 1000 Genomes Project, TCGA, GTEx, UK Biobank)
  • Strong programming skills in Python and experience with scientific/bioinformatics libraries
  • Experience working in high-performance computing environments (Kubernetes, SGE, LSF, SLURM)
  • Practical knowledge of cloud computing platforms, particularly AWS or GCP
  • Familiarity with workflow orchestration languages such as WDL and Nextflow

What Sets You Apart

  • Experience in clinical diagnostics development and regulatory requirements
  • Track record of developing and deploying production-grade bioinformatics pipelines
  • Publications or patents in relevant fields
  • Strong communication skills and ability to collaborate across technical and non-technical teams

Join Natera and be part of a team that's transforming healthcare through cutting-edge genomic analysis.

#LI-TH1 #LI-Remote

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$116,200$145,300 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

Interested in this job?

Application deadline: Open until filled

Logo of Natera

Natera

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

See more jobs
Date PostedJune 27th, 2025
Job TypeFull Time
LocationUS Remote
Salary$116,200 - $145,300
Exciting remote opportunity (requires residency in United States) for a Senior Bioinformatician/Computational Biologist at Natera. Offering $116,200 - $145,300 (full time). Explore more remote jobs on FlexHired!

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