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Natera

Senior Site Reliability Engineer

Job Summary

The role involves designing, developing, and maintaining scalable cloud infrastructure, focusing on AWS and Kubernetes platforms. The candidate should have extensive experience with AWS services, Terraform, and cloud security practices, along with scripting and infrastructure validation skills. Responsibilities include automating secure infrastructure to support bioinformatics workflows, ensuring operational excellence and cost efficiency. The position is within a collaborative team dedicated to advancing genetic testing and diagnostics at Natera.

Required Skills

Cloud Infrastructure
Terraform
Python
DevOps
Observability
Kubernetes
Docker
Monitoring
Prometheus
Grafana
AWS Services
Helm
Loki
Secrets Management
AWS Security
Bash scripting
EKS
Lambda
CloudWatch
Infrastructure Testing
AWS CDK
Karpenter
CloudTrail

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
Life Insurance
401K
Commuter Benefits
Employee Referral Program
Paid Leave
Disability Plans
Fertility Care

Job Description

Position Summary:

The Senior Site Reliability Engineer within the Platform group will join a tight-knit, cross-functional team of scientists and engineers. This team is dedicated to developing a scalable and robust platform that will underpin Natera's next generation of clinical assays. You will be instrumental in the design, development, and architecture of software products relevant to the clinical laboratory, while also contributing to cutting-edge R&D, bioinformatics, and high-performance computing initiatives. We're seeking an experienced candidate who is proficient across various tech stacks, passionate about building robust and scalable software, and excited about their work directly impacting the care of millions of patients.

The Senior DevOps & Cloud Infrastructure Engineer will design and implement our AWS and Kubernetes platform. You'll architect and automate scalable, secure infrastructure that supports our bioinformatics workflows while maintaining operational excellence and cost optimization.

Required Skills:

  • BS degree in computer science or equivalent program

  • 7+ years of software development experience with AWS services (EC2, S3, VPC, IAM)

  • Expert-level Terraform skills, including module development and state management

  • Experience with EKS, Karpenter, and Kubernetes operators

  • Expertise in AWS security best practices and compliance frameworks

  • Experience with monitoring and observability tools

  • Knowledge of cost allocation tags and AWS Cost Explorer

  • Experience with infrastructure validation and testing

  • Strong scripting skills in Python or Bash

Experience with:

  • Terraform, AWS CDK

  • EKS, Karpenter, Helm

  • AWS Lambda, CloudWatch, CloudTrail

  • Vault or AWS Secrets Manager

  • Prometheus, Grafana, Loki

  • AWS Organizations and IAM

  • Docker, Kubernetes

  • Terratest for infrastructure validation

#LI-TH1 #LI-Remote

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$137,200$171,500 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

Interested in this job?

Application deadline: Open until filled

Logo of Natera

Natera

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

See more jobs
Date PostedJune 28th, 2025
Job TypeFull Time
LocationUS Remote
Salary$137,200 - $171,500
Exciting remote opportunity (requires residency in United States) for a Senior Site Reliability Engineer at Natera. Offering $137,200 - $171,500 (full time). Explore more remote jobs on FlexHired!

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