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Datavant

Senior/Staff Cloud Infrastructure Engineer

Job Summary

The role involves designing, optimizing, and securing cloud infrastructure, with an emphasis on cloud migration, multi-cloud networking, security, and automation. The candidate should have extensive experience in cloud architecture, especially in AWS and Azure, and be skilled in automating infrastructure provisioning and implementing security standards. Collaboration with security, infrastructure, and platform teams is essential to ensure best practices and governance. The position requires deep expertise in cloud technologies, cost management, and disaster recovery, supporting the company's transition to a cloud-first model.

Required Skills

Cloud Infrastructure
Networking
Identity and Access Management
Automation
Cost Optimization
Security
Infrastructure as Code
Monitoring and Alerting
Security Controls
Storage
Disaster Recovery
Hybrid Cloud
Compute
Multi-cloud Connectivity

Benefits

Equal Employment Opportunity
Accommodation for Disabilities
Workplace Diversity
Health Screenings
Vaccination Requirements

Job Description

Datavant is a data platform company and the world’s leader in health data exchange. Our vision is that every healthcare decision is powered by the right data, at the right time, in the right format.

Our platform is powered by the largest, most diverse health data network in the U.S., enabling data to be secure, accessible and usable to inform better health decisions. Datavant is trusted by the world’s leading life sciences companies, government agencies, and those who deliver and pay for care.

By joining Datavant today, you’re stepping onto a high-performing, values-driven team. Together, we’re rising to the challenge of tackling some of healthcare’s most complex problems with technology-forward solutions. Datavanters bring a diversity of professional, educational and life experiences to realize our bold vision for healthcare.

What We’re Looking For

We are seeking a Staff Cloud Infrastructure Engineer to play a key role in designing, optimizing, and securing the underlying cloud infrastructure that powers our organization’s cloud environments. As we transition from an on-premise colo environment to a cloud-first model, this role will be instrumental in architecting scalable, secure, and resilient infrastructure, ensuring seamless workload migration, and integrating new cloud environments into our ecosystem.

This role focuses on core cloud infrastructure, including networking, identity and access management, security, storage, compute, and cross-cloud integrations. You will collaborate closely with security, infrastructure, and platform engineering teams to ensure our cloud environment adheres to best practices, governance frameworks, and automation-first principles.

What You Will Do

  • Design, implement, and optimize cloud-native infrastructure using best practices for security, scalability, and high availability.
  • Assist with on-prem to cloud migration efforts, ensuring smooth transitions and minimal downtime.
  • Integrate external cloud environments into the organization’s cloud footprint, ensuring security and consistency.
  • Develop and implement hybrid-cloud and cross-cloud connectivity strategies to ensure interoperability.
  • Architect and optimize multi-cloud networking (AWS VPCs, Azure VNets, Transit Gateway, ExpressRoute, PrivateLink, Direct Connect, VPNs).
  • Manage DNS, routing, and traffic management to enable secure, low-latency communication across cloud environments.
  • Collaborate with security teams to enforce Zero Trust networking, IAM, and encryption standards.
  • Implement and manage security controls, including AWS GuardDuty, Security Hub, Azure Defender, NSGs, SGs, WAF, and IAM policies.
  • Automate cloud infrastructure provisioning using Terraform and Ansible, ensuring repeatability and compliance.
  • Implement policy-based automation (AWS SCPs, Azure Policy) to maintain governance across cloud environments.
  • Optimize cloud spending with FinOps best practices, leveraging tools such as AWS Cost Explorer, Azure Cost Management, and right-sizing strategies.
  • Support observability teams with infrastructure monitoring and alerting using CloudWatch, Datadog and Splunk.

What You Need to Succeed

You have deep expertise in cloud infrastructure architecture and operations, with a strong background in AWS and Azure. You have successfully migrated workloads to the cloud, designed secure, scalable, and automated environments, and integrated new cloud platforms into existing ecosystems. You work well across teams, balancing strategic planning with hands-on execution, and thrive in a fast-paced environment where collaboration, problem-solving, and continuous improvement are key.

  • 10+ years of experience in cloud infrastructure engineering, platform engineering, or infrastructure architecture.
  • Strong expertise in cloud infrastructure, including networking, security, compute, storage, and IAM.
  • Experience migrating workloads from on-prem to cloud and integrating new cloud environments into existing architectures.
  • Deep understanding of multi-cloud networking (AWS VPCs, Azure VNets, Transit Gateway, ExpressRoute, PrivateLink, DNS, hybrid connectivity).
  • Hands-on experience with Infrastructure as Code and automation (Terraform and Ansible).
  • Strong security knowledge, including IAM, encryption, network security, and compliance frameworks (SOC2, HITRUST, NIST, FedRAMP).
  • Experience managing multi-account cloud governance and security policies (AWS Organizations, Azure Policy, SCPs).
  • Excellent problem-solving skills for cloud networking, security, and performance optimization.

What Helps You Stand Out

  • Experience in hybrid or multi-cloud environments with on-prem connectivity.
  • Hands-on experience with cloud storage solutions (Amazon S3, Azure Blob, EFS, FSx).
  • Knowledge of multi-region architecture and disaster recovery strategies.
  • Background in cloud cost optimization and FinOps methodologies.
  • Experience with cloud-native identity management (AWS IAM Identity Center, Entra ID, RBAC).

We are committed to building a diverse team of Datavanters who are all responsible for stewarding a high-performance culture in which all Datavanters belong and thrive. We are proud to be an Equal Employment Opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, or other legally protected status.

At Datavant our total rewards strategy powers a high-growth, high-performance, health technology company that rewards our employees for transforming health care through creating industry-defining data logistics products and services.

The range posted is for a given job title, which can include multiple levels. Individual rates for the same job title may differ based on their level, responsibilities, skills, and experience for a specific job.

The estimated total cash compensation range for this role is:
$132,000$195,000 USD

To ensure the safety of patients and staff, many of our clients require post-offer health screenings and proof and/or completion of various vaccinations such as the flu shot, Tdap, COVID-19, etc. Any requests to be exempted from these requirements will be reviewed by Datavant Human Resources and determined on a case-by-case basis. Depending on the state in which you will be working, exemptions may be available on the basis of disability, medical contraindications to the vaccine or any of its components, pregnancy or pregnancy-related medical conditions, and/or religion.

This job is not eligible for employment sponsorship.

Datavant is committed to a work environment free from job discrimination. We are proud to be an Equal Employment Opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, or other legally protected status. To learn more about our commitment, please review our EEO Commitment Statement here. Know Your Rights, explore the resources available through the EEOC for more information regarding your legal rights and protections. In addition, Datavant does not and will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay.

At the end of this application, you will find a set of voluntary demographic questions. If you choose to respond, your answers will be anonymous and will help us identify areas for improvement in our recruitment process. (We can only see aggregate responses, not individual ones. In fact, we aren’t even able to see whether you’ve responded.) Responding is entirely optional and will not affect your application or hiring process in any way.

Datavant is committed to working with and providing reasonable accommodations to individuals with physical and mental disabilities. If you need an accommodation while seeking employment, please contact us at [email protected]. We will review your request for reasonable accommodation on a case-by-case basis.

For more information about how we collect and use your data, please review our Privacy Policy.

Interested in this job?

Application deadline: Open until filled

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Datavant

Join Datavant’s network of networks, including 300+ real-world data partners, more than 70,000 hospitals and clinics, and 70% of the top 100 largest health systems.

See more jobs
Date PostedMay 28th, 2025
Job TypeFull Time
LocationRemote - United States
Salary$132,000 - $195,000
Exciting remote opportunity (requires residency in United States) for a Senior/Staff Cloud Infrastructure Engineer at Datavant. Offering $132,000 - $195,000 (full time). Explore more remote jobs on FlexHired!

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