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Natera

Manager, Variant Curation

Job Description

POSITION SUMMARY
As the Manager of Variant Curation, you will help the Director/Sr. Director of Variant Curation oversee the operational responsibilities of the team to ensure curation tasks are performed efficiently and accurately, while also ensuring sufficient and well-trained staff are available to meet operational needs.


PRIMARY RESPONSIBILITIES:

● Alongside the Director/Sr. Director of Variant Curation, attend operational and cross-functional meetings with members of the wet-lab, Lab Directors, Quality Assurance, product managers, and Engineering teams, etc., and provide periodic updates to ensure alignment within the supervisors and production team.
● Monitor production metrics developed by the Director/Sr. Director of Variant Curation, and assign priorities to the production team to ensure turnaround times are met.
● Initiate and manage compliance with QA, including NCRs, CAPAs, competencies, and documentation.

● Improve the troubleshooting turnaround by delegating and managing resources based on business needs.
● Review genetic variant data: interpret medical literature, online variant databases, and other references to classify variants according to the internal standard operating procedures (SOPs).
● Provide operational support for the curation team and discuss clinical issues with Lab Directors as necessary.
Supervisory:
● Establish goals, review and approve assigned work and provide mentorship to further develop team members.
● In conjunction with other supervisors, oversee individual productivity metrics and hold periodic check-ins to ensure team members meet expectations and deliverables.
● Help onboard and guide junior supervisors and collaborate with other supervisors to prioritize work, validate new products, and improve workflows.
● Perform various administrative tasks related to personnel management
● Assist with corrective action plans and remedial training when necessary.
● Maintain ongoing competency and support periodic updates to procedures and workflows.
● Ensure timely completion of training requirements, including HIPAA and PHI security training


QUALIFICATIONS
● Master’s degree required (PhD preferred) in genetics or related field.
● 5+ years of supervisory or team leadership experience in genetics/variant curation or related field (industry or clinical).
● 3+ years of experience in variant curation.
● 2+ Experience in a CLIA-certified laboratory setting analyzing and interpreting genetic/genomic data.


KNOWLEDGE, SKILLS, AND ABILITIES:
● Expertise in the variant review and interpretation.
● Excellent problem solving, conflict resolution, and decision-making skills.
● Good written and oral communication skills.
● Knowledge of CAP, CLIA, and state regulations (California and New York preferred).


PHYSICAL DEMANDS & WORK ENVIRONMENT:
● Prolonged periods of working on a computer/laptop and occasional standing or sitting for extended periods.
● Duties may occasionally require working shifts, weekends, or overtime.
Travel required for this position:
☒ Yes, up to 10%

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$116,400$145,500 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

Interested in this job?

Applications are no longer being accepted for this job.

Logo of Natera

Natera

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

See more jobs
Date PostedApril 1st, 2025
Job TypeFull Time
LocationUS Remote
Salary$116,400 - $145,500
Application DeadlineExpired
Exciting remote opportunity (requires residency in United States) for a Manager, Variant Curation at Natera. Offering $116,400 - $145,500 (full time). Explore more remote jobs on FlexHired!

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